Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation.
The Rutgers-led study, spanning seven years, employed some of the most advanced approaches available in the scientific toolbox, including growing human brain cells from stem cells and transplanting them into mouse brains.
The work illustrates the potential of a new approach to studying brain disorders, scientists said.
https://medicalxpress.com/news/2022-11-gene-mutation-autism-overstimulate-brain.html